TRETINOIN 0.05%
Brand Johnson
&Amp; Johnson
Uses Anti Aging/
Anti Acne
Prescription Retin-A first became popular more than 20 years
ago as an acne treatment. But doctors and patients soon noticed another
benefit, one with enormous impact on those who were looking for a way to keep
skin vibrant and smooth.
Retin-A users reported improvements in skin texture,
including diminished wrinkles and brown spots. Early studies soon confirmed its
anti-aging effects. In 1988, Dr. Voorhees and his colleagues at Michigan
published the first double-blind study of Retin-A’s effect on photodamaged skin
and found that all 30 patients who completed the 16-week study showed
statistically significant improvement.
Retin-A, the drug known generically as retinoic acid or
tretinoin, is derived from vitamin A. Retinol, a less potent form of Retin-A,
also has some strong science to support its effectiveness.
Skin cells contain retinoid receptors that help regulate how
the cell functions. As people age, their cells behave more erratically. “But
consistent use of Retin-A helps normalize the cells,” said Dr. Min-Wei
Christine Lee, a dermatologist in Walnut Creek, Calif.
Retin-A can improve skin texture and fade dark spots and
freckles because it causes skin cells to turn over more rapidly. It shrinks
dilated pores and improves cell turnover within the pores so they are less
likely to clog and become blackheads and whiteheads. But what has earned
Retin-A its long-held reputation is its ability to affect the retention of
collagen.
Collagen is what gives skin its structure, firmness and
elasticity. Repeated sun exposure breaks down collagen and, with age, cells
produce less and less collagen to repair the damage. Skin wrinkles, sags and
loses fullness.
Retin-A does double duty in helping to boost collagen.
According to research at Michigan, it has the potential to stop photoaging
before it starts. “The retinoids prevent the rise of collagenase after UV
exposure,” Dr. Voorhees said. Collagenase is what breaks down collagen.
But regular use of a retinoid product also increases the
amount of new collagen formed, research has found, and that new collagen will
last for years.
Retin-A cream is used for:
Treating acne. It may also be used for other conditions as
determined by your doctor.
Retin-A cream is a vitamin A derivative. How it exerts its
beneficial effects against acne is not fully known. Tretinoin appears to
increase skin-cell turnover and to reduce the tendency for skin cells to stick
together. This reduces the formation of acne and allows quicker healing of acne
that does develop.
Before using Retin-A cream:
Some medical conditions may interact with Retin-A cream.
Tell your doctor or pharmacist if you have any medical conditions, especially
if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are
breast-feeding
if you are taking any prescription or nonprescription
medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other
substances
if you have eczema, an abnormally high white blood cell
count, or a sunburn
Some MEDICINES MAY INTERACT with Retin-A cream. Because
little, if any, of Retin-A cream is absorbed into the blood, the risk of it
interacting with another medicine is low.
Ask your health care provider if Retin-A cream may interact
with other medicines that you take. Check with your health care provider before
you start, stop, or change the dose of any medicine.
How to use Retin-A cream:
Use Retin-A cream as directed by your doctor. Check the
label on the medicine for exact dosing instructions.
Retin-A cream is for external use only.
Remove all cosmetics with a mild soap before applying
Retin-A cream. Gently dry the area. Wait 20 to 30 minutes to make sure that
your skin is completely dry.
Apply a thin film of medicine to the affected area. Rub in
gently.
Wash your hands immediately after using Retin-A cream.
If you miss a dose of Retin-A cream, skip the missed dose
and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have
about how to use Retin-A cream.
Important safety information:
Retin-A cream is for external use only. Avoid getting
Retin-A cream in your eyes, nose, or mouth. If you get Retin-A cream in your
eyes, rinse thoroughly with water.
Retin-A cream may cause you to become sunburned more easily.
Avoid the sun, sunlamps, or tanning booths until you know how you react to
Retin-A cream. Use a sunscreen or wear protective clothing if you must be outside
for more than a short time.
For the first 2 to 3 weeks of treatment, your skin condition
may appear to worsen. This is expected. Do not stop using Retin-A cream at this
time.
Talk with your doctor before you use any other medicines or
products on your skin. While you are using Retin-A cream, you may use
cosmetics.
Do not apply Retin-A cream to skin that is sunburned. Wait
until the burn is fully healed before using Retin-A cream.
Do NOT use more than the recommended dose or use for longer
than prescribed without checking with your doctor.
Avoid using other topical medication, cosmetics, or other
products that have a strong drying effect. If you have dry skin from using
these products, allow your skin to "rest" before using Retin-A cream.
Do not use Retin-A cream for any condition other than that
for which it was prescribed.
Weather extremes, such as windy or cold weather, may
irritate your skin more while you are using Retin-A cream.
Retin-A cream may cause harm if it is swallowed. If you may
have taken it by mouth, contact your poison control center or emergency room
right away.
PREGNANCY and BREAST-FEEDING: If you become pregnant,
contact your doctor. You will need to discuss the benefits and risks of using
Retin-A cream while you are pregnant. It is not known if Retin-A cream is found
in breast milk. If you are or will be breast-feeding while you use Retin-A
cream, check with your doctor. Discuss any possible risks to your baby.
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